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Log In Sign Up. Acid-Base Analysis of Antacid Tablets. Asmha Asmha From stomach acid to the soda we drink and our household cleaners. Our stomach acid is a mixture of many different compounds that assist in the breakdown of foods that we ingest. One of the major components is hydrochloric acid HCl of approximately 0. We need that acid in our stomachs to help food digestion, but often times in the absence of food there is an excess amount of acid in our stomachs.
The power of an antacid tablet is determined by the amount of HCl that it can neutralize, more acid neutralized equals a more effective antacid tablet.
In this laboratory experiment, you will determine the amount of HCl neutralized by two different commercially available antacid tablets. To do this we will perform what is called a titration, a lab technique which is used to determine the amount of a compound by reacting it with a standard of known concentration. In this experiment, you will perform a slight variation on a titration called a back-titration.
Titration Consider a solution that has an unknown concentration of an HCl. If we take our solution that contains an unknown amount of acid, we can react it incrementally with base of a known concentration, we keep adding base until all of the acid is completely used up.
How do we know when the acid is completely gone? We use an acid-base indicator, which is a compound that changes color depending on the pH or acid concentration of the solution. We have many indicators at our disposal, so in the process of adding our base to our unknown solution, a color change will occur, which indicates the point at which all of the acid has been used up. Another way of saying that is that the moles of base added equals the moles of acid present in the solution.
You collect the following pieces of equipment: A buret to measure the amount of standard solution you will be addingan erlenmeyer flask to perform the experiment inand a bottle with acid-base indicator. First, you weigh the tablet of antacid you remove from the bottle, then you disperse it in a small amount of water and add in This step is so that the tablet will dissolve completely.
You also put in drops of an acid-base indicator. In the beaker, you now have the inactive ingredients in the tablet and the excess amount of acid that did not react with the antacid tablet. You then place As you swirl the flask, you add standard NaOH solution dropwise to the flask. As you add NaOH, it reacts completely with the acid in the beaker. When the indicator changes color, all of the HCl has been used up and you stop the titration, this occurs when you have added Now is the time for calculations.
You grab your trusty calculator, pencil and paper and determine a little bit about your ancient antacid tablets. A back-titration means that we will add an excess of a standard HCl solution to our antacid tablet first, then neutralize this solution back to the indicator color change. We do this because it is difficult to dissolve the antacid tablets otherwise.
This allows us to determine the amount of HCl that did not react and through calculation, determine three values that tell us about the effectiveness of the antacid for neutralizing acid, the volume of HCl neutralized, the moles of HCl neutralized, and the grams of HCl neutralized per gram of antacid tablet. Obtain two different antacid tablets from the lab instructor or TA.Over-the-counter antacids provide some relief from the symptoms of acid indigestion.
The difference between the end point and the equivalence point is known as the titration error. Repeat the procedure with another brand of antacid.
Show all calculations clearly. A student dissolves 0. The student boils the mixture and then allows it to cool. Finally, the student adds bromophenol blue indicator to the mixture, which turns yellow. Suppose that How many equivalents of antacid are present in the sample? Find the number of equivalents of antacid present per gram of antacid.
It is preferable to use tablets that are white and have no added flavor. Should either of these solutions come in contact with skin or eyes, rinse thoroughly with water. Allow enough time for the boiled antacid solution to come to room temperature before touching it. With a mortar and pestle, crush one tablet of antacid to as fine a powder as possible.
Weigh out between 0. Record the mass of the antacid sample to 0. Part B: Preparation of Burets Obtain two burets from the stockroom and, with soap and water, wash them with a brush. Rinse them well with deionized water When the buret is cleaned properly, there should be no water droplets clinging to the inside of the buret. Label them accordingly and record their concentrations as indicated on the label.
It is important that the concentration of the acid and base are not diluted with any of the water left over from cleaning. Note that bubbles take up space, so make sure to dislodge any bubbles that might be stuck in the tip of the buret by lightly tapping the tip or by letting a portion of the solution run rapidly through the tip.
9: Evaluating the Cost-Effectiveness of Antacids (Experiment)
We sometimes use them to treat this because antacids are a mild base that can neutralize acids in our stomachs, such as HCl. The purpose of this lab is to see how well each antacid neutralize hydrochloric acid. Procedure: 1. Record the exact molarity as they appear on the stock bottles. Determine the mass of each of you antacid tablets. Dispense 25 mL of HCl solution into the Erlenmeyer flask, and then add one of the antacid tablets to the flask.
Bring the solution to a boil to dispel any undissolved CO2. Add two or three drops of an indicator to our antacid mixture. Titrate antacid mixture with the NaOH solution until we have reached the end point of the indicator used.
Calculate grams active ingredient: 3. This is because it neutralized the most moles of HCl per gram of antacid.
Analysis of an Antacid
The active ingredient in this antacid is Magnesium Hydroxide. As the result, I prefer to buy Phillips antacid to resist heartburn. Learn the Estimated Price for a Custom Paper writers online. See Pricing. Submit Task and Start Chatting.
Analysis of an Antacid.If you find yourself allocated a lengthy lab report, it is essential to include a bottom line paragraph to sum up your strategies and successes for your visitor. A in closing restates your plans and methods, entails any last information and facts and information whether or not you could properly resolve the considerations caused from your play around.
Acid-Base Titrations: Analysis of Antacid Tablets Essay Sample
At any time you begun your report with a preliminary section, temporarily restate every thing you reported there. Take note all plans with the experiment: What question or requests were definitily you desiring to provide answers to?
You would probably include your forecast of methods the sodium quantity would modify the cold point, as outlined by your recent know-how about biochemistry.
Produce a simple breakdown of the methods you used by your try things out. Be aware the key tools and equipment and materials for your test, as well as strategies accustomed to have information.
In addition to the breakdown of techniques, feature a quick outline of why you consider all those solutions to secure your computer data.
Comprise and Explore Remaining Material The heart from your lab report targets the data from the tests — including each one of the facts you obtained and also a specific exploration of that files. For example, if assessing the details from an play with it to look for the solidity of formaldehyde rendered a median consequence of 8. Your judgment must give a brief clarification of the items the actual info from a play with it indicates. Discuss any fads within your info, and note regardless whether any irregularities in the outcomes helped bring up more thoughts.
Also report any achievable causes of error inside your data files including your assessment. Now, on your own realization, examine the data using your desired goals and estimates for the experiment. Area whether the outcomes of your experiment made it possible for someone to provide answers to the inquires that you just simply set out within release.Setting up and Performing a Titration
If you are flourishing, status so. Or even, give a prospective description for why your play around was not able to respond to these things, and advise a way that may be utilised in one more test to better answer them. Categories Uncategorized. Best ways to Write a Lab Report Conclusions If you find yourself allocated a lengthy lab report, it is essential to include a bottom line paragraph to sum up your strategies and successes for your visitor.
This experiment was performed to learn the technique of acid-base titration and to compare the efficiency of commercially available antacids by looking at their weight of HCl and weight of antacid values. The analysis of antacid tablets was highlighted in this experiment. The efficiency of antacid tablets was determined and compared when the number of grams of HCl can be neutralized by 1 gram of the tablet was found.
First, the two antacid tablets Kremil-S were crushed and weighed to the nearest 0. Then, transferred into a mL flask and added Then, the antacid was dissolved in the acid. After that, the two drops of phenolphthalein indicator were added and was mixed thoroughly.
Lastly, the antacid mixture was titrated with 0. Recorded the final volume of NaOH used. Here, two trials were done. After the procedures, the weight of HCl that reacted with 1 gram of antacid tablet was calculated and found the result of 0. With the recovered amount of HCl, it was found out that the antacid tablet Kremil-S that has been tested were not so efficient. The experiment that has been conducted only shows how antacid tablets counteract acidity by reacting with the excess hydrochloric acid in the stomach and its effectiveness as one of the most widely used self-prescribed medicine.
Antacid tablets are probably one of the most widely used self-prescribed medicines. They are taken to relieve the medically underlined conditions of heartburn on acid indigestion and sour stomach. Excessive hydrochloric acid in the stomach causes a feeling of discomfort and a burning sensation beneath the breastbone resulting from a spastic backflow of this acid content into the esophagus. Antacid tablets counteract acidity by reacting with the excess hydrochloric acid in the stomach.
These components neutralize the excess stomach acids. Antacids are designed to raise the pH level of the stomach from a too-acidic state. Neutral pH is 7, while the normal stomach acid level usually is 2 to 4. Antacids contain sodium, calcium, magnesium or aluminum, or a combination of these. Any of these ingredients can raise pH levels by neutralizing stomach acid.
The efficiency of antacid tablets may be determined and compared by finding the number of grams of HCl that can be neutralized by 1 gram of the tablet. The higher the amount of HCl that can be neutralized by one gram of the tablet, the more efficient is the antacid tablet.
In determining the efficiency of an antacid tablet, the volume of unreacted HCl in the antacid mixture is titrated with NaOH. The two Kremil-S tablets were crushed using mortar and pestle. After, the crushed antacids were weighed to the nearest 0. Also measured Dissolved the Kremil-S in the acid as completely as possible and added two drops of phenolphthalein indicator into the mixture and mixed thoroughly. Then, the antacid mixture was titrated with 0.Experiment Analysis of Antacid Tablets.
Report Sheets for Experiment pdf format. This week you will determine the antacid base content of some commercially available antacids. The analysis you will perform is called a back-titration and it is described briefly below:. The Chemistry:. Various commercial products are available for the relief of heartburn and indigestion.
All of these remedies are little more than weak bases that react with and neutralize stomach acid, which is primarily hydrochloric acid, HCl. Milk of magnesia magnesium hydroxide, Mg OH 2 is a common antacid, normally sold as a suspension in water, that uses hydroxide ions as the base:. A more elaborate base is found in Rolaidswhich contains aluminum sodium dihydroxycarbonate, and uses both carbonate and hydroxide ions to neutralize "excess stomach acid":.
Not only do commercially available antacids vary in chemical content, they also vary in the amount of acid-neutralizing substance they contain. Determining the best buy among the various antacids requires a knowledgeable chemist.
You will participate in a class project to determine the best antacid product per dollar from a group of selected products. You will be asked to analyze a product, report the base content, and calculate the relative effectiveness per dollar. The Methodology: Back Titration.
The amount of this acid consumed by the antacid is equal to the amount of base in the antacid sample:. Your results can be reported as:. Conclusion and Error Analysis:. In your lab notebook, based on the data below, write a brief conclusion stating which brand of antacid you would chose 1 sentence and the criteria you used to make this decision sentences.
Possible criteria to consider are cost per unit specify which unittablet size, active ingredients, dosage and recommended frequency. The mole of acid neutralized was calculated from the list of active ingredients on the container, not from titration data. Because some active and inactive ingredients in the some brands affect the titration, your values may differ.
In the lab report, you should report values obtained from analysis i. Tums Regular. Tums Xtra. Tums Ultra. Rolaids Extra. Top Care.Please join StudyMode to read the full document. Pure water is said to be neutral, with a pH close to 7. This happens when these nerves are exposed. Antacids are taken by mouth and work by neutralizing excess stomach acid. They contain ingredients such as aluminum hydroxide, calcium carbonate, magnesium hydroxide, and sodium bicarbonate, alone or in various combinations.
Antacid products may also contain other ingredients such as simethicone, which relieves gas. Antacids differ in how quickly they work and how long they provide relief. Those that dissolve rapidly in the stomach, such as magnesium hydroxide and sodium bicarbonate, bring the fastest relief. Antacids that contain calcium carbonate or aluminum dissolve more slowly and can take up to 30 minutes to begin working. The longer an antacid stays in the stomach, the longer it works. Those that contain calcium carbonate or aluminum Vibhuti Walia, our Chemistry faculty without whose constructive guidance this term paper would not have been a success.
Her valuable advice and suggestions for the corrections, modifications and improvement did enhance the perfection in performing my job well. I am obliged to Lovely Proffesional University for providing the best of facilities and environment to bring out our innovation and spirit of inquiry through this venture.
Last but not the least I thank all My Friends and Section Mates, without their prompt support my efforts would have been in vain. Vipin Raghuwanshi Table of content 1. Acknowledgement 2. Abstract 3. Introduction 4. Mechanism of reaction 5. Indications 6.